Expression in fibroblast culture of the satellited-X chromosome associated with familial sex-linked mental retardation
- 1 February 1980
- journal article
- research article
- Published by Springer Science and Business Media LLC in Human Genetics
- Vol. 53 (2), 267-269
- https://doi.org/10.1007/bf00273509
Abstract
The satellited-X chromosome previously shown in lymphocyte culture to be associated with certain types of sex-linked mental retardation has, for the first time, been demonstrated in cultured skin fibroblasts and lymphocytes from two affected males and an obligate carrier female. These findings provide a basis for reliable diagnosis of female carriers and for the development of prenatal diagnosis.This publication has 9 references indexed in Scilit:
- Heritable fragile sites on human chromosomes II. Distribution, phenotypic effects, and cytogenetics.1979
- Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture.1979
- Delivery of Plasticizer from Standard Intravenous-Administration SetsNew England Journal of Medicine, 1978
- Fragile Sites on Human Chromosomes: Demonstration of Their Dependence on the Type of Tissue Culture MediumScience, 1977
- Familial X-linked mental retardation with an X chromosome abnormality.Journal of Medical Genetics, 1977
- Banding analysis of abnormal karyotypes in spontaneous abortion.1973
- Non-condensation of one segment of a chromosome No. 2 in a male with an otherwise normal karyotype (and severe hypospadias)Human Genetics, 1970
- A marker X chromosome.1969
- EFFECT OF 5-BROMODEOXYURIDINE ON MAMMALIAN CHROMOSOMESProceedings of the National Academy of Sciences of the United States of America, 1961