INCREASE OF THE PROSTAGLANDIN PRECURSOR, ARACHIDONIC ACID, IN AMNIOTIC FLUID DURING SPONTANEOUS LABOUR
- 1 December 1977
- journal article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 84 (12), 937-940
- https://doi.org/10.1111/j.1471-0528.1977.tb12524.x
Abstract
Concentrations of free arachidonic acid have been measured by gas liquid chromatography in amniotic fluid obtained during spontaneous labour at term. Levels of arachidonic acid ranged from 0·14 to 2·2 μg/ml and increased significantly (P<0·01) with advancing cervical dilatation. Concentrations of arachidonic acid showed no significant relation to concentrations of either prostaglandin F or 13,14-dihydro-15-keto-prostaglandin F. These findings are discussed with respect to the role of arachidonic acid in the control of prostaglandin biosynthesis during human parturition.Keywords
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