Structure and conformation of epimers derived from the antibiotic teicoplanin.
- 1 January 1984
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 37 (10), 1204-1208
- https://doi.org/10.7164/antibiotics.37.1204
Abstract
Basic hydrolyses carried out on the glycopeptide antibiotic teicoplanin or its acidic hydrolysis products gave rise to an epimeric species which retained little antibiotic activity. The detailed structure of a sample epimer was determined using 1H NMR spectroscopy.This publication has 4 references indexed in Scilit:
- NUCLEAR MAGNETIC-RESONANCE STUDIES ON THE ANTIBIOTIC AVOPARCIN - CONFORMATIONAL PROPERTIES IN RELATION TO ANTIBACTERIAL ACTIVITY1984
- Teicoplanin, antibiotics from Actinoplanes teichomyceticus nov. sp. VI. Chemical degradation: physico-chemical and biological properties of acid hydrolysis products.The Journal of Antibiotics, 1984
- Teichomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. IV. Separation and characterization of the components of teichomycin (teicoplanin).The Journal of Antibiotics, 1984
- Detailed binding sites of the antibiotics vancomycin and ristocetin A: determination of intermolecular distances in antibiotic/substrate complexes by use of the time-dependent NOEJournal of the American Chemical Society, 1983