Phosphoinositides. 1. Configuration of the inositol phosphate in liver phosphatidylinositol
- 1 June 1960
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 75 (3), 495-500
- https://doi.org/10.1042/bj0750495
Abstract
Liver phosphatidylinositol was hydrolyzed to give glycerylphosphorylinositol, alkaline hydrolysis of which gives a mixture of inositol monophosphate (30-40%) and glycerophosphate. Hydrolysis of synthetic glycerol 1-(inositol-2-phosphate) gives a similar mixture. Steric effects in the hydrolysis are discussed and it is concluded that liver phosphatidylinositol has the inositol 1- or 2-phosphate structure.Keywords
This publication has 12 references indexed in Scilit:
- Synthesis and Properties of 1-Glyceryl-2-Myo-Inosityl Phosphate: Synthesis of 1-Glyceryl-2-myo-inosityl PhosphateNature, 1959
- Separation of glycerylphosphoryl inositol and related compounds on ion-exchange columnsBiochemical Journal, 1959
- CHEMICAL NATURE OF MONOPHOSPHOINOSITIDESJournal of Biological Chemistry, 1958
- A COLUMN CHROMATOGRAPHIC SEPARATION OF CLASSES OF PHOSPHOLIPIDESJournal of Biological Chemistry, 1957
- A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUESJournal of Biological Chemistry, 1957
- A MONOPHOSPHOINOSITIDE OF LIVERJournal of Biological Chemistry, 1956
- A further study of inositol-containing lipidsBiochimica et Biophysica Acta, 1954
- [Isolation of a crystalline phosphatide from the beef myocardium; glycero-inosito-phosphatic acid].1954
- A STUDY OF INOSITOL-CONTAINING LIPIDESJournal of Biological Chemistry, 1954
- Detection of Phosphate Esters on Paper ChromatogramsNature, 1953