Serum Interleukin 6, C-Reactive Protein and Pancreatic Secretory Trypsin Inhibitor (Psti) as Acute Phase Reactants After Major Thoraco-Abdominal Surgery

Abstract
We measured serum immunoreactive interleukin 6 (IL-6) levels in patients after major thoraco-abdominal surgery and compared them with changes in serum C- reactive protein (CRP) and pancreatic secretory trypsin inhibitor (PSTI) levels. Serum IL-6 levels were elevated earlier than serum CRP or PSTI. There were significant relationships between the peak levels of serum IL-6 and the operation time (p<0.05) or the volume of blood loss during surgery (p0.01), there was no relationship between the peak levels of IL-6 and PSTI.