Orizabins V−VIII, Tetrasaccharide Glycolipids from the Mexican Scammony Root (Ipomoea orizabensis)

Abstract

An extensive investigation of the so-called jalapin resinoid obtained from roots of the Mexican scammony, Ipomoea orizabensis, using high field NMR spectroscopy led to the characterization of six glycosides, including the known scammonins I (1) and II (2) and four new tetrasaccharides of jalapinolic acid, orizabins V−VIII (3−6). All the isolates (1−6) were found to be weakly cytotoxic toward human oral epidermoid carcinoma (KB).