Albumin-IgG complexes in human serum and plasma that inhibit blood platelet adhesion.
- 1 December 1981
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 78 (12), 7750-7753
- https://doi.org/10.1073/pnas.78.12.7750
Abstract
Macromolecular albumin-IgG complexes were isolated from human serum and characterized immunologically. These complexes are present in plasma and appear to be normal constituents of blood. The complexes can be demonstrated in normal serum and plasma by immunoelectrophoresis and rocket immunoelectrophoresis, and by use of a 2-step radioimmunologic binding test. The albumin-IgG complexes inhibit adhesion of human platelets to glass and account for 12-16% of the total protein in serum.Keywords
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