A Trinuclear Heterobimetallic Ru(II)/Pt(II) Complex as a Chemodosimeter Selective for Sulfhydryl-Containing Amino Acids and Peptides
- 4 June 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 125 (26), 7802-7803
- https://doi.org/10.1021/ja034891x
Abstract
A trinuclear heterobimetallic Ru(II)/Pt(II) complex, cis-{Ru(phen)2[CN−Pt(DMSO)Cl2]2} (phen = 1,10-phenanthroline), is able to function as a “switch-on” luminescent chemodosimeter for sulfhydryl-containing amino acids and peptides via specific binding of the amino acids/peptides with the Pt(II) centers and the subsequent cleavage of the Ru(II)−Pt(II) cyano-bridge.Keywords
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