ANURIA FOLLOWING HEMOLYTIC REACTION TO BLOOD TRANSFUSION; RECOVERY FOLLOWING SPLANCHNIC BLOCK

Abstract

A case presented in which a hemolytic reaction and nine days'' anuria followed transfusion of blood of the homologous group. The role of the Rh agglutinogen involved and its causal mechanism in hemolytic transfusion reactions was first reported by A. S. Wiener and the author in 1940. Accrued evidence is offered in favor of a vaso-constrictive renal element in transfusion anurias similar to that of reflex anurias. Splanchnic block, variously reported as successful in reflex anuria, was performed in this case with immediate institution of diuresis and eventual recovery of patient. While offered as an adjunct to therapy of transfusion anurias the author stresses the importance of carefully checking patient''s chemical balance, including fluid intake, blood N, proteins, chlorides, Na and CO2 combining power. These values need judicious therapeutic adjustment, even after diuresis is established.