Affinity and Phosphorylation Constants for the Inhibition of Esterases by Organophosphates
- 22 May 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 144 (3621), 992-993
- https://doi.org/10.1126/science.144.3621.992
Abstract
Equations based on the assumption of a reversible first step in the reaction between organophosphate inhibitors and esterases are proposed for the bimolecular rate constant which now includes an affinity constant and a phosphorylation constant. The treatment applies when the inhibition reaction follows first-order kinetics.Keywords
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