Synthesis of 3-Hydroxy-2-Methylene Carbonyl Compounds - Effect of Catalyst and Substrate on Reaction Rate
- 1 September 1988
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 18 (13), 1565-1572
- https://doi.org/10.1080/00397918808081314
Abstract
3-Hydroxyquinuclidine enhances the rate of formation of the title compounds whereas the acetylated derivative is a poor catalyst. A comparative study shows that methyl vinyl ketone is more reactive than methyl acrylate in the Baylis-Hillman reaction.Keywords
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