Glycosides from Muscari comosum. 1. Eucosterol glycoside and structure of its methanolysis products

Abstract

A mixture of at least 4 glycosides was isolated from bulbs of M. comosum. Acidic methanolysis of this mixture yielded a crystalline fraction consisting of 4 diols differing in configuration at the epimerizable C-20 and/or C-24 centers. Benzoylation of this diol fraction allowed the isolation of 1 pure dibenzoate, mp [melting point] 175-176.degree. C, to which a structure was assigned on the basis of chemical and spectral evidence. One of the aglycone moieties was 27-norlanostane triterpene eucosterol.