The isolation and identifiction of 5-Hydroxypiperidine-2-carboxylic Acid from Leucaena glauca Benth

Abstract

The isolation and identification of 5-hydroxypiperidine-2-carboxylic acid from the leaves of L. glauca Benth. by procedures using ion-exchange resins and chromatography are described. This imino acid has been synthesized and the resulting diastereo-isomers separated by chromatographic techniques. The stereochemistry of the natural and the synthetic compounds is discussed.