Biosynthese Folsäure- und NAD-analoger Verbindungen
- 1 January 1967
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 348 (Jahresband), 455-459
- https://doi.org/10.1515/bchm2.1967.348.1.455
Abstract
In bacteria the inhibition by sulfanilamide can be overcome with either [rho]-aminobenzoic acid, [rho]-aminosalicylic acid, 6-aminonicotinic acid or 2-aminopyrimidine-5-carboxylic acid. With radioactive labelled 6-aminonicotinic acid we found that this compound is converted by bacterial cells to a folic acid analogue. 6-aminonicotinic acid is also converted to an analogue of NAD.This publication has 3 references indexed in Scilit:
- Pyridine Nucleotide Metabolism: Mechanism of Action of the Niacin Antagonist, 6-AminonicotinamideJournal of Biological Chemistry, 1958
- Mikrobiologische Synthese der Folinsäure aus 2-Amino-6-oxy-pteridinaldehyd-8 und p-Aminobenzoyl-l-glutaminsäureZeitschrift für Naturforschung B, 1949
- Anti-sulphanilamide Activity of 2-Aminopyrimidine-5-carboxylic AcidNature, 1944