Short-Echo Time Proton MR Spectroscopy in the Presence of Gadolinium
- 1 September 2001
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Journal of Computer Assisted Tomography
- Vol. 25 (5), 705-712
- https://doi.org/10.1097/00004728-200109000-00007
Abstract
The purpose of this work was to quantify the impact of contrast agents on short-TE single-voxel 1H MR spectroscopy (MRS) diagnosis of recurrent brain tumors. Short-TE 1H MRS was performed in 49 patients with biopsy-proven brain tumors and 14 control subjects. Eight patients (nine paired exams) were examined before and after administration of Gd-DTPA (interval approximately 5–7 min). Tumor spectra showed increased choline/creatine ratio (Cho/Cr; p 1 Proton MRS with TE of 30 ms may safely be used in combined contrast-enhanced MRI/MRS protocols. Further study is required with long-TE MRS because of the prolonged T2 of Cho.Keywords
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