Infections of susceptible and resistant mouse strains with herpes simplex virus type 1 and 2
- 1 September 1980
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 65 (3-4), 219-227
- https://doi.org/10.1007/bf01314538
Abstract
The spread of HSV of type 1 and 2 was investigated after intraperitoneal, intraplantar and intracerebral infections of resistant (C57/bl) and susceptible (NMRI) mice. The virus spreads after i.p. infection to the spleen and the liver to the same extent in both strains of mice. However, virus is eliminated earlier in resistant mice. Intracerebral infections revealed a peculiar type of resistance of C57/bl mice especially for type 2 of HSV. HSV multiplies in the thymus at the early stage of infection and can be detected in this organ in sick mice of NMRI strain. HSV-1 and 2 can be detected in the spinal cord of C57/bl mice without sickness or death of these animals.This publication has 48 references indexed in Scilit:
- Macrophage Extrinsic Antiviral Activity during Herpes Simplex Virus InfectionJournal of General Virology, 1980
- Resistance of nude mice to herpes simplex virus and correlation with in vitro production of interferonCellular Immunology, 1979
- In vitro acquisition of resistance against herpes simplex virus by permissive murine macrophagesArchiv für die gesamte Virusforschung, 1979
- The effect of Dextransulfate 500 on the pathogenesis of herpes simplex virus infections in weanling miceArchiv für die gesamte Virusforschung, 1978
- Genetics of natural resistance to herpesvirus infections in miceNature, 1975
- Thymidine-, uridine- and choline-kinase in rabbit kidney cells infected with herpesvirus hominis, type I and IIArchiv für die gesamte Virusforschung, 1972
- Effect of Murine Strain and Viral Strain on the Pathogenesis of Lymphocytic Choriomeningitis Infection and a Study of Footpad ResponsesThe Journal of Infectious Diseases, 1971
- RESTRICTION OF HERPES SIMPLEX VIRUS BY MACROPHAGESThe Journal of Experimental Medicine, 1971
- Zwei genetisch determinierte Varianten eines Herpes-simplex-StammesArchiv für die gesamte Virusforschung, 1962
- STUDIES ON THE INNATE RESISTANCE OF MICE TO INFECTION WITH MOUSEPOXImmunology & Cell Biology, 1960