Microwave irradiation of human brain tissue: production of microscopic slides within one day.
Open Access
- 1 May 1988
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 41 (5), 590-593
- https://doi.org/10.1136/jcp.41.5.590
Abstract
A three step method using microwave irradiation enabled microscopic slides of human brain tissue to be obtained within one working day: steps 1 and 2 hardened and solidified brain tissue; step 3 completed formalin fixation. The efficacy and precision of the method was compared with slides of conventionally processed brain tissue that had been fixed in formalin for six weeks. The microscopic quality of the sections was excellent with good presentation of brain tissue and equalled that of conventionally processed slides.Keywords
This publication has 16 references indexed in Scilit:
- Microwave-cryostat technique for neuroanatomical studiesJournal of Neuroscience Methods, 1987
- Major Improvement in Microscopic-Image Quality of Cryostat Sections: Combining Freezing and Microwave-Stimulated FixationAmerican Journal of Clinical Pathology, 1987
- Perfusion-fixation of the human brain for immunohistochemistry: comparison with immersion-fixationJournal of Neuroscience Methods, 1987
- A method of rapid fixation of large biopsy specimens using microwave irradiationPathology, 1986
- Formaldehyde fixation.Journal of Histochemistry & Cytochemistry, 1985
- Changes in the levels of cyclic nucleotides in rat brain during the sleep-wakefulness cycleBrain Research, 1981
- Preliminary report: microwave fixation of human tissues.1974
- Microwave Irradiation as a Generator of Heat for Histological FixationStain Technology, 1974
- Fast Fixation of Surgical Pathology SpecimensLaboratory Medicine, 1972
- Histological fixation by microwave heating.Journal of Clinical Pathology, 1970