Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene
Open Access
- 1 August 2000
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 267 (16), 5191-5197
- https://doi.org/10.1046/j.1432-1327.2000.01588.x
Abstract
Clostridium perfringens phospholipase C (PLC), also called α‐toxin, is the major virulence factor in the pathogenesis of gas gangrene. The toxic activities of genetically engineered α‐toxin variants ...Keywords
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