Palladium(II)-catalysed oxidation of allylic amines with molecular oxygen

Abstract

The palladium(II)-catalysed oxidative cyclization of the adducts of N-Boc-protected allylic amines with methyl glyoxylate proceeds well in the presence of molecular oxygen as the stoichiometric oxidant without the need of a co-oxidant, if Me₂SO is used as the solvent.