Possible Contribution of Melatonin to the Timing of the Luteinizing Hormone Surge
- 11 June 1987
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 316 (24), 1550-1551
- https://doi.org/10.1056/nejm198706113162418
Abstract
To the Editor: Marshall and Kelch were asked during the discussion that followed their seminar (Dec. 4 issue)1 about factors in the central nervous system that may contribute to the timing of the luteinizing hormone (LH) surge. Dr. Marshall replied that "some central mechanism in the rat clearly increases either the frequency or the amount of GnRH [gonadotropin-releasing hormone] secreted in the early evening. There is no evidence of such a daily signal in humans." On the contrary, such a factor has been clearly demonstrated in many mammals and may also apply to humans.Melatonin, the hormone secreted by the . . .Keywords
This publication has 8 references indexed in Scilit:
- Gonadotropin-Releasing Hormone: Role of Pulsatile Secretion in the Regulation of ReproductionNew England Journal of Medicine, 1986
- The Circadian Pattern of Melatonin and Its Positive Relationship with Progesterone in WomenJournal of Clinical Endocrinology & Metabolism, 1986
- FALL IN NOCTURNAL SERUM MELATONIN DURING PREPUBERTY AND PUBESCENCEThe Lancet, 1984
- Biological rhythm of the luteinizing hormone surge in womenFertility and Sterility, 1982
- Selectivity of Melatonin Pituitary Inhibition for Luteinizing Hormone-Releasing HormoneNeuroendocrinology, 1982
- The Pineal and Its Hormones in the Control of Reproduction in Mammals*Endocrine Reviews, 1980
- The Pineal OrganNew England Journal of Medicine, 1977
- Inhibition of Ovulation by Melatonin in the Cyclic Rat1Endocrinology, 1973