Physical activity and physiological cardiac remodelling in a community setting: the Multi-Ethnic Study of Atherosclerosis (MESA)
- 26 October 2009
- Vol. 96 (1), 42-48
- https://doi.org/10.1136/hrt.2009.178426
Abstract
Objective: To evaluate the association of physical activity with left ventricular structure and function in the general population in a community setting. Design: Cross-sectional study. Setting: The Multi-Ethnic Study of Atherosclerosis (MESA), a population-based study of subclinical atherosclerosis. Participants: A multiethnic sample of 4992 participants (aged 45–84 years; 52% female) free of clinically apparent cardiovascular disease. Interventions: Physical activity induces beneficial physiological cardiac remodelling in a cross-sectional study of non-athlete individuals. Main Outcome Measures: Left ventricular mass, volumes and function were assessed by cardiac magnetic resonance imaging. Physical activity, defined as intentional exercise and total moderate and vigorous physical activity, was assessed by a standard semiquantitative questionnaire. Results: Left ventricular mass and end-diastolic volume were positively associated with physical activity (eg, 1.4 g/m2 (women) and 3.1 g/m2 (men) greater left ventricular mass in the highest category of intentional exercise compared with individuals reporting no intentional exercise; p = 0.05 and pConclusions: In a community-based population free of clinically apparent cardiovascular disease, higher physical activity levels were associated with proportionally greater left ventricular mass and end-diastolic volume and lower resting heart rate.Keywords
This publication has 31 references indexed in Scilit:
- Age-Related Left Ventricular Remodeling and Associated Risk for Cardiovascular OutcomesCirculation: Cardiovascular Imaging, 2009
- The Relationship of Left Ventricular Mass and Geometry to Incident Cardiovascular EventsJournal of the American College of Cardiology, 2008
- The Association Between Physical Activity and Subclinical Atherosclerosis: The Multi-Ethnic Study of AtherosclerosisAmerican Journal of Epidemiology, 2008
- The Athleteʼs HeartSports Medicine, 2008
- Cardiovascular Function in Multi-Ethnic Study of Atherosclerosis: Normal Values by Age, Sex, and EthnicityAmerican Journal of Roentgenology, 2006
- Adaptation of cardiac morphology and function to endurance and strength trainingScandinavian Journal of Medicine & Science in Sports, 2002
- Morphology of the “athlete's heart” assessed by echocardiography in 947 elite athletes representing 27 sportsThe American Journal of Cardiology, 1994
- Left ventricular dimensions and mass using magnetic resonance imaging in female endurance athletesThe American Journal of Cardiology, 1992
- Prognostic Implications of Echocardiographically Determined Left Ventricular Mass in the Framingham Heart StudyNew England Journal of Medicine, 1990
- Association of echocardiographic left ventricular mass with body size, blood pressure and physical activity (the Framingham study)The American Journal of Cardiology, 1990