Plasma Lipid Transfer in Fish-Eye Disease

Abstract

Fish-eye disease is a familial condition characterized by corneal opacities and dyslipoproteinemia with, i.a., pronounced enrichment of plasma low density lipoprotein (LDL) with triglycerides. Cholesterol ester and triglyceride transferase activities in lipoprotein-free plasma, measured in 2 patients with fish-eye disease were normal. This indicates that a deficiency of plasma lipid transfer protein is not involved in the abnormal composition of LDL in fish-eye disease.