Therapeutic evaluation of the oral retinoid Ro 10-9359 in several non-psoriatic dermatoses
- 1 November 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 103 (5), 483-488
- https://doi.org/10.1111/j.1365-2133.1980.tb01662.x
Abstract
Patients (45) suffering from various genodermatoses and erythematous, scaling, non-psoriatic dermatoses were treated orally with the aromatic derivative of retinoic acid, Ro 10-9359 (Tigason) [ethyl-all-trans-9-(4-methoxy-2,3,6-trimethylphenyl)-3, 7-dimethyl-2, 4, 6, 8 nonatetraenoate]. In the genodermatoses the best results were obtained in ichthyosis, keratodermias and Darier''s disease (95.6% good to excellent). Among the erythematous scaling diseases, treatment was effective in lichen planus, parapsoriasis and pityriasis rubra pilaris (53.3% good to excellent results). In comparison with therapies previouslY employed Ro 10-9359 was more effective. No serious side effects were noted.This publication has 9 references indexed in Scilit:
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