PITUITRIN ANEMIA
- 30 January 1937
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 118 (2), 241-250
- https://doi.org/10.1152/ajplegacy.1937.118.2.241
Abstract
The injection of 200 units per kilo of pituitrin in rabbits causes a severe macrocytic, hyper-chromic anemia. This anemia results from water retention due to the antidiuretic action of pituitrin and is hemolytic in character. The serum osmotic pressure falls rapidly, reaching levels so low as to be isosmolar with 0.561% NaCl. Measures designed to maintain the serum electrolyte composition within normal limits after the administration of pituitrin will prevent this anemia.This publication has 3 references indexed in Scilit:
- The fate of the antidiuretic principle of postpituitary extracts in vivo and in vitro1The Journal of Physiology, 1935
- EXPERIMENTAL SODIUM LOSS ANALOGOUS TO ADRENAL INSUFFICIENCY: THE RESULTING WATER SHIFT AND SENSITIVITY TO HEMORRHAGEAmerican Journal of Physiology-Legacy Content, 1934
- A thermal method of measuring the vapour pressure of an aqueous solutionProceedings of the Royal Society of London. Series A, Containing Papers of a Mathematical and Physical Character, 1930