Abstract
Na N-hexylethyl barbituric acid in dilute solns. when applied to the frog''s heart paralyzes the post-ganglionic vagus nerve fibers. These results on frogs support the finding of Gruber, Haury and Gruber on the terrapin heart that though the action may be on the ganglion, it is not confined to this structure but also involves the post-ganglionic nerve fibers of the cardiac vagus nerves.