Platinum-Induced Filamentous Growth in Escherichia coli

Abstract
Certain group-VIIIB transition metal compounds were found to inhibit cell division inE. coli. causing marked filamentous growth. Gram -negative bacilli were the most sensitive to this effect, whereas gram-positive bacilli responded only at near-toxic levels of the metal. None of the cocci tested showed any apparent effect. Cytokinesis (cross -septation) can be initiated by removal or decrease of platinum, but not by treatment with pantoyl lactone, divalent cations, or a temperature of 42 C.