ABSENCE OF A SEROLOGICALLY DETECTABLE ASSOCIATION OF MURINE β2-MICROGLOBULIN WITH THE EMBRYONIC F9 ANTIGEN

Abstract

SUMMARY The association of murine β₂-microglobulin to the early embryonic F9 antigen has been investigated by indirect immunofluorescence and by radioimmunoassay. Although some cell lines carry both types of molecules, the β₂-microglobulin was not found expressed on primitive teratocarcinoma cells, where F9 antigen was primarily detected. It is concluded that the low m.w. (12,000 daltons) subunit that was reported to be associated to the F9 antigen is not the adult β₂)-microglobulin.