The operator-binding domain of λ repressor: structure and DNA recognition
- 1 July 1982
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 298 (5873), 443-447
- https://doi.org/10.1038/298443a0
Abstract
The structure of the operator-binding domain of the phage .lambda. repressor protein was determined at 3.2 .ALPHA.NG resolution. This domain contains an extended N-terminal arm and 5 .alpha.-helices. Model-building studies of the repressor-operator complex suggest that .alpha.-helices, especially the N-terminal parts of these helices, may provide a useful surface for protein-DNA interactions. [Phage .lambda. infects Escherichia coli.].Keywords
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