Structure of a human common cold virus and functional relationship to other picornaviruses
- 1 September 1985
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 317 (6033), 145-153
- https://doi.org/10.1038/317145a0
Abstract
We report the first atomic resolution structure of an animal virus, human rhinovirus 14. It is strikingly similar to known icosahedral plant RNA viruses. Four neutralizing immunogenic regions have geen identified. These, and corresponding antigenic sequences of polio and foot-and-mouth disease viruses, reside on external protrusions. A large cleft on each icosahedral face is probably the host cell receptor binding site.This publication has 57 references indexed in Scilit:
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