Aragusterol C: A novel halogenated marine steroid from an Okinawan sponge,Xestospongia sp., possessing potent antitumor activity
- 1 February 1994
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 50 (2), 134-136
- https://doi.org/10.1007/bf01984951
Abstract
A novel chlorinated steroid, aragusterol C, was isolated from an Okinawan marine sponge of the genusXestospongia. The compound strongly inhibited the proliferation of KB cells in vitro, and also showed potent in vivo antitumor activity against L1210 cells in mice. The complete structure of aragusterol C was determined by spectroscopic analysis and X-ray crystallographic analysis.This publication has 4 references indexed in Scilit:
- Aragusterol a: A potent antitumor marine steroid from the okinawan sponge of the genus, XestospongiaTetrahedron Letters, 1993
- Three unprecedented chloro steroids from the Maui sponge Strongylacidon sp.: kiheisterones C, D, and EThe Journal of Organic Chemistry, 1993
- Marine natural productsNatural Product Reports, 1992
- Chlorinated withanolides from Withania somnifera and Acnistus breviflorusPhytochemistry, 1981