On the specificity of autoantibodies present in colon cancer patients.
- 1 June 1966
- journal article
- Vol. 10 (6), 507-15
Abstract
223 sera of patients having a colonic cancer or other diseases were examined for the presence of antibodies agglutinating tanned sheep erythrocytes coated with saline extracts of human colonic cancers. Some patients' sera were also investigated for precipitating antibodies. Many positive results were found, mainly but not only, in colonic cancer patients' sera. By absorption studies the antibodies found in these sera have been shown to be directed against an antigen present not only in the tumours but also in normal and foetal tissues as well as in the microsomal fraction of the intestine. The chemical nature of the antigen is still under investigation.This publication has 15 references indexed in Scilit:
- Fluorescent antibodies to human cancer-specific DNA and nuclear proteinsCancer, 1965
- ETUDE IMMUNOLOGIQUE DES EPITHELIOMAS MAMMAIRES HUMAINS1965
- Isoantibodies to Human Cancer Cells in Cancer Patients Following Cancer HomotransplantsThe Journal of Immunology, 1964
- Carcinoma of the colon in ulcerative colitisCancer, 1964
- INDUCTION OF METASTASES BY TREATMENT WITH CARCINOSTATIC AGENTS .2. DEPRESSION OF HOST RESISTANCE AND ANTIBODY PRODUCTION1964
- STUDIES IN TUMOR AUTO-IMMUNITY1960
- CARCINOMA AND ULCERATIVE COLITIS - CLINICAL-PATHOLOGIC STUDY .1. CANCER DEATHS1958
- Specific Tumor AntigensAdvances in Cancer Research, 1958
- Studies of normal and malignant tissue antigens.1956
- The localization of antilymphosarcoma antibodies in the Murphy lymphosarcoma of the rat.1954