Coexistent Endocervical Adenocarcinoma and Mucinous Adenocarcinoma of Ovary: A Clinicopathologic Study of Four Cases

Abstract

We present a series of four women with endocervical adenocarcinoma who were found to harbor synchronous mucinous neoplasms of the ovary. In each case, "in situ" components were found in each site, lending weight to the belief that the lesions represented separate primary lesions rather than metastatic disease. Atypical epithelial lesions in the fallopian tubes (two cases) and endometrium (one case) give further support for the lesions being expressions of "multifocal" neoplastic transformation in embryologically related epithelia.