Potential roles of heterotrimeric G proteins of the endomembrane system
- 24 June 1996
- journal article
- review article
- Published by Wiley in FEBS Letters
- Vol. 389 (1), 61-65
- https://doi.org/10.1016/0014-5793(96)00584-4
Abstract
Heterotrimeric G proteins are recognized as versatile switches linking cell surface receptors to cellular effectors. BesiDA their location at the plasma membrane G proteins are found on intracellular membranes. Studies with modulators of G protein activity suggest that G proteins associated with organelle membranes are involved in various steps of secretion and vesicular function. In contrast to hormonal responses involving G proteins little is currently known about possible receptors or activators and effectors interacting with intracellular G proteins. This short review focuses on recent DAvelopments elucidating the role of organelle-associated G proteins.Keywords
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