Removal of metronidazole by haemodialysis
- 1 August 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 67 (8), 553
- https://doi.org/10.1002/bjs.1800670807
Abstract
Summary: The removal of the anti-anaerobic antibiotic metronidazole has been studied in oliguric patients. The drug and its principal metabolite are rapidly removed by haemodialysis so that the plasma concentration quickly falls below the therapeutic range. Hence a further dose of metronidazole would be needed after dialysis to restore an adequate plasma concentration.Keywords
This publication has 2 references indexed in Scilit:
- Determination of metronidazole and its two major metabolites in biological fluids by high pressure liquid chromatography.British Journal of Clinical Pharmacology, 1978
- Bioassay of Metronidazole with Either Anaerobic or Aerobic IncubationThe Journal of Infectious Diseases, 1975