SUCCINIC ACID DECARBOXYLATION SYSTEM IN PROPIONIBACTERIUM PENTOSACEUM AND VEILLONELLA GAZOGENES I

Abstract
The decarboxylation of succinate to propionate and CO2 was studied with cell-free extracts of P. pentosaceum and V. gazogenes. The total reaction is CoA and ATP dependent, and activation of succinate and lower fatty acids (hydroxamate formation) was shown. Transsuccinylase, acyl-CoA deacylases, succinyl-propionyl CoA transphorases and acetyl-succinyl transphorase activity was shown. Acetate- and succinate-activating enzyme systems were separated. Reaction mechanisms are discussed.

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