BILIRUBIN AND UROBILINS IN GERMFREE, EX-GERMFREE, AND CONVENTIONAL RATS
Open Access
- 1 December 1960
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 112 (6), 975-981
- https://doi.org/10.1084/jem.112.6.975
Abstract
No urobilinogens are present in the feces or urine of germfree rats. After contamination of germfree animals with feces from conventional animals the exgermfree rats produced urobilins to the same extent as conventional animals on the same diet. The negative urobilin test turned positive in germfree animals infected with a single Clostridium-like microorganism isolated from the intestinal contents of rats with urobilins in the feces. The output increased in these monoinfected animals after superinfection with a strain of E. coli but never reached the values of conventional animals.Keywords
This publication has 5 references indexed in Scilit:
- Composition of the urobilin group in urine bile, and feces and the significance of variations in health and disease.1959
- LIGHTWEIGHT STAINLESS STEEL SYSTEMS FOR REARING GERMFREE ANIMALS*Annals of the New York Academy of Sciences, 1959
- VITAMIN K DEFICIENCY IN GERMFREE RATS*Annals of the New York Academy of Sciences, 1959
- Seminar: the pyrrol pigments and hemoglobin catabolism.1956
- A note on the disturbance of the haemoglobin metabolism of the rat by sulphanilamideBiochemical Journal, 1949