1,4-Addition of enolates to α,β-unsaturated ketones within a micro reactor
- 19 April 2002
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Lab on a Chip
- Vol. 2 (2), 62-64
- https://doi.org/10.1039/b202210a
Abstract
We demonstrate the formation of a series of diketone enolates and their subsequent reaction with α,β-unsaturated carbonyl compounds in order to prepare a variety of Michael adducts. In all cases, the conversions observed within a micro reactor were greater than those obtained in batch.Keywords
This publication has 8 references indexed in Scilit:
- The aldol reaction of silyl enol ethers within a micro reactorLab on a Chip, 2001
- The synthesis of peptides using micro reactorsChemical Communications, 2001
- Rapid prototyping of glass and PDMS microstructures for micro total analytical systems and micro chemical reactors by microfabrication in the general laboratoryAnalytica Chimica Acta, 2001
- Spatial Concentration Profiling within Channel Networks in Transparent Microreactors Using a Digital Imaging MethodPublished by Springer Nature ,2001
- The preparation of a series of nitrostilbene ester compounds using micro reactor technologyThe Analyst, 2000
- The use of a novel microreactor for high throughput continuous flow organic synthesisSensors and Actuators B: Chemical, 2000
- Theoretical considerations of chemical reactions in micro-reactors operating under electroosmotic and electrophoretic controlThe Analyst, 1999
- The fabrication of micro-porous silica structures for micro-reactor technologyAnalytical Communications, 1998