LUPUS ERYTHEMATOSUS DISSEMINATUS

Abstract

A case of lupus erythematosus with visceral involvement is reported. The patient was 20 yrs. old and was observed for 20 successive mos. from onset to termination. It is unusual in that so many of the multiple features of this disease were observed in 1 patient. The clinical attributes consisted of photosensitivity, cutaneous eruption, alopecia, arthritis, pericarditis, endocarditis, petechiae, papilledema, pleuritis, pneumonitis, nephritis, transient uremia, splenomegaly, hepatomegaly, ascites, peripheral edema, gastrointestinal disturbances, prolonged fever, anemia, leukocytosis, delirium, convulsions and coma. The significant morphological changes consisted of atypical verrucous endocarditis (Lib man-Sacks) with superimposed acute bacterial endocarditis, adhesive pericarditis, disseminated vascular lesions, polyserositis, focal and diffuse glomerular nephritis and interstitial pancreatitis.