Expression and Characterization of a DNase I-Fc Fusion Enzyme
Open Access
- 1 April 1999
- journal article
- Published by Elsevier
- Vol. 274 (14), 9738-9743
- https://doi.org/10.1074/jbc.274.14.9738
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Improved Potency of Hyperactive and Actin-resistant Human DNase I Variants for Treatment of Cystic Fibrosis and Systemic Lupus ErythematosusJournal of Biological Chemistry, 1998
- Hyperactivity of Human DNase I VariantsPublished by Elsevier ,1998
- Mutational analysis of human DNase I at the DNA binding interface: Implications for DNA recognition, catalysis, and metal ion dependenceProtein Science, 1998
- Engineering Hyperactive Variants of Human Deoxyribonuclease I by Altering Its Functional MechanismBiochemistry, 1997
- Immunoadhesins as research tools and therapeutic agentsCurrent Opinion in Immunology, 1997
- The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasoneClinical and Experimental Immunology, 1996
- Engineering actin-resistant human DNase I for treatment of cystic fibrosis.Proceedings of the National Academy of Sciences, 1996
- Management of Pulmonary Disease in Patients with Cystic FibrosisNew England Journal of Medicine, 1996
- Effect of Aerosolized Recombinant Human DNase on Exacerbations of Respiratory Symptoms and on Pulmonary Function in Patients with Cystic FibrosisNew England Journal of Medicine, 1994
- Efficacy and Safety of Short-term Administration of Aerosolized Recombinant Human Deoxyribonuclease in Patients with Cystic FibrosisAmerican Review of Respiratory Disease, 1993