A Method for the In Vitro Toxicity Testing of Dental Restorative Materials
- 1 October 1977
- journal article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 56 (10), 1285-1290
- https://doi.org/10.1177/00220345770560103401
Abstract
An in vitro method of toxicity testing of dental restorative materials is described in which their clinical usage is closely simulated. The test material was separated from the cells by either a synthetic filter or dentine slice. Toxic effects were quantitated by determining changes in enzyme activity by scanning and integrating microdensitometry.Keywords
This publication has 12 references indexed in Scilit:
- Biological testing of dental restorative materialsJournal of Oral Rehabilitation, 1977
- Anin vitromethod for toxicity evaluation of water-soluble substancesActa Odontologica Scandinavica, 1976
- A quantitative microspectrophotometric study of the lead precipitation reaction for the histochemical demonstration of acid phosphataseJournal of Molecular Histology, 1975
- The lysosomal permability test modified for toxicity testing with cultured heart endothelioid cellsJournal of Molecular Histology, 1975
- A permeability test for the study of mitochondrial injury inin vitro cultured heart muscle and endothelioid cellsJournal of Molecular Histology, 1975
- Electron Microscopic Study of the Cytotoxicity of Cadmium and Mercury In VitroJournal of Dental Research, 1975
- Kinetic and quantitative evaluation of material cytotoxicity in vitroOral Surgery, Oral Medicine, Oral Pathology, 1973
- Tissue culture and toxicologyFood and Cosmetics Toxicology, 1971
- Lining materials with special reference to Dropsin. A comparative studyBritish Dental Journal, 1970
- HISTOCHEMICAL STUDIES OF LYSOSOMES AND LYSOSOMAL ENZYMES IN VIRUS-INFECTED CELL CULTURESThe Journal of Experimental Medicine, 1965