A repeat sequence, GGGTTA, is shared by DNA of human herpesvirus 6 and Marek's disease virus
Open Access
- 1 December 1988
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 62 (12), 4824-4827
- https://doi.org/10.1128/jvi.62.12.4824-4827.1988
Abstract
Some regions of the genomes of human B-lymphotrophic virus (HBLV), also designated as human herpesvirus 6, and Marek9s disease virus were found to hybridize to each other under moderate to stringent conditions, scoring from 10 to 30% base-pair mismatch. Nucleotide sequence analysis showed that a 6-base-pair repetitive sequence, GGGTTA (DR2), present in the IRS-IRL junction region of the Marek9s disease virus genome, was also reiterated in the HBLV genome. The function(s) of such a sequence is unknown, but this is the first report of homology between HBLV and a nonhuman herpesvirus. ImagesThis publication has 32 references indexed in Scilit:
- IDENTIFICATION OF HUMAN HERPESVIRUS-6 AS A CAUSAL AGENT FOR EXANTHEM SUBITUMThe Lancet, 1988
- DNA HOMOLOGY BETWEEN A NOVEL HUMAN HERPESVIRUS (HHV-6) AND HUMAN CYTOMEGALOVIRUSThe Lancet, 1988
- Ultrastructural Characterization of a New Human B Lymphotropic DNA Virus (Human Herpesvirus 6) Isolated From Patients With Lymphoproliferative DiseaseJNCI Journal of the National Cancer Institute, 1987
- DIVERSE TROPISM OF HUMAN B-LYMPHOTROPIC VIRUS (HUMAN HERPESVIRUS 6)The Lancet, 1987
- A NOVEL LYMPHOTROPIC HERPESVIRUSThe Lancet, 1987
- ISOLATION OF HUMAN LYMPHOTROPIC HERPESVIRUSES FROM UGANDAThe Lancet, 1987
- Isolation of a New Virus, HBLV, in Patients with Lymphoproliferative DisordersScience, 1986
- Minor DNA homology between herpesvirus of Turkey and Marek's disease virus?Virology, 1979
- Anatomy of herpes simplex virus DNA. II. Size, composition, and arrangement of inverted terminal repetitionsJournal of Virology, 1975
- Inverted Repetitions in the Chromosome of Herpes Simplex VirusCold Spring Harbor Symposia on Quantitative Biology, 1974