Prothrombin Activation Cycle.
- 1 March 1958
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 97 (3), 642-644
- https://doi.org/10.3181/00379727-97-23831
Abstract
The prothrombin activation cycle consists of a sequence described by the following Prothrombin (sensitive to Ca + Ac-globulin + lung thromboplastin)[forward arrow] Prothrombin derivative I (not sensitive to Ca + Ac-globulin + lung thromboplastin) [forward arrow] Prothrombin derivative II (sensitive to Ca + Ac-globulin + lung thromboplastin) [forward arrow] Thrombin. Solutions of prothrombin standing at 4[degree]C go through most of this cycle, the prothrombin molecule alone possessing the peculiar properties that enables it to do this.Keywords
This publication has 4 references indexed in Scilit:
- Formation of Prothrombin From Autoprothrombin by Means of Liver MitochondriaAmerican Journal of Physiology-Legacy Content, 1955
- Formation of Prothrombin Derivatives From Purified ProthrombinAmerican Journal of Physiology-Legacy Content, 1951
- STUDIES ON PROTHROMBIN: PURIFICATION, INACTIVATION WITH THROMBIN, AND ACTIVATION WITH THROMBOPLASTIN AND CALCIUMJournal of Biological Chemistry, 1948
- FACTORS WHICH INFLUENCE THE ACTIVITY OF PURIFIED THROMBINAmerican Journal of Physiology-Legacy Content, 1942