Clomid or Nafoxidine Administered to Neonatal Rats Causes Reproductive Tract Abnormalities
- 8 July 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 197 (4299), 164-165
- https://doi.org/10.1126/science.877546
Abstract
A single injection of either Clomid or Nafoxidine in neonatal rats causes multiple abnormalities of the reproductive tract of the adult female animal. These anomalies include cystic ovaries, ovarian hypoplasia, hilus cell tumors, oviductal hyperplasia, pyometra, epithelial metaplasia, uterine cystic hyperplasia, and tumors of the uterus.Keywords
This publication has 8 references indexed in Scilit:
- Nuclear Binding and Retention of the Receptor Estrogen Complex: Relation to the Agonistic and Antagonistic Properties of Estriol11Endocrinology, 1977
- Die Keimdrüsenfunktion der Ratte nach prae- oder postnataler Injektion verschiedener HormoneArchiv für Gynäkologie, 1976
- Oestrogen receptors and antagonism of steroid hormone actionNature, 1974
- Conversion of Androstenedione to Estrone by Neural Tissues from Fetal and Neonatal Rats12Endocrinology, 1974
- Estrogen receptor · anti-estrogen complex: Atypical binding by uterine nuclei and effects on uterine growthSteroids, 1973
- Persistent Estrus and Altered Estrogen Sensitivity in Rats Treated Neonatally with Clomiphene CitrateFertility and Sterility, 1971
- Ontogeny of the Estrogen Receptor during Early Uterine DevelopmentScience, 1970
- Modification of ovulatory mechanisms by postnatal administration of estrogen to the ratAmerican Journal of Physiology-Legacy Content, 1963