Raising Ca2+in L6 myotubes mimics effects of exercise on mitochondrial biogenesis in muscle
Open Access
- 19 February 2003
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 17 (6), 675-681
- https://doi.org/10.1096/fj.02-0951com
Abstract
Skeletal muscle adapts to endurance exercise with an increase in mitochondria. Muscle contractions generate numerous potential signals. To determine which of these stimulates mitochondrial biogenesis...Keywords
Funding Information
- National Institute on Aging (AG00425)
This publication has 40 references indexed in Scilit:
- Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscleBiochemical and Biophysical Research Communications, 2002
- Nuclear activators and coactivators in mammalian mitochondrial biogenesisBiochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 2002
- Peroxisome proliferator–activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesisJournal of Clinical Investigation, 2000
- cDNA Cloning and mRNA Analysis of PGC-1 in Epitrochlearis Muscle in Swimming-Exercised RatsBiochemical and Biophysical Research Communications, 2000
- Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1Cell, 1999
- A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive ThermogenesisCell, 1998
- Activation of the human mitochondrial transcriptionfactor A gene by nuclear respiratory factors: a potential regulatory linkbetween nuclear and mitochondrial gene expression in organellebiogenesis.Proceedings of the National Academy of Sciences, 1994
- NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells.Genes & Development, 1990
- Energy metabolism in contracting rat skeletal muscle: adaptation to exercise trainingAmerican Journal of Physiology-Cell Physiology, 1987
- Biochemical adaptation of mitochondria, muscle, and whole-animal respiration to endurance trainingArchives of Biochemistry and Biophysics, 1981