A possible conformation for double-stranded polynucleotides.
- 1 September 1976
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 73 (9), 2959-2963
- https://doi.org/10.1073/pnas.73.9.2959
Abstract
A model is presented for double-stranded polynucleotides which involves side-by-side meshing of the 2 strands rather than double helical intertwining. The sugar-phosphate backbone has a twisted strip-like character, yet base-pairing of the Watson-Crick type is still possible. Structural features of the basic model are described, and coordinates are presented for a representative example. The structure has reasonable stereochemical contacts and can be shown to produce a fiber diffraction pattern with x-rays not unlike that of the B form of DNA.This publication has 8 references indexed in Scilit:
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