The rarity of basal cell epithelioma of the anus was demonstrated by Guess1 in 1935. He found no tumors of this type listed in the records of 150,000 biopsies at the State Institute for Malignant Disease at Buffalo. There was no mention of this tumor in a group of reports on 2,000 anal and rectal malignant tumors which he collected from the literature. Guess reported 1 personally observed case of anal basal cell carcinoma. The tumor was a small lesion. Four local excisions of supposed external hemorrhoids and tabs had been done prior to histologic examination of the tissue. This tumor was treated with 1,400 millicurie hours of interstitial radiation in the form of gold radon seeds. Healing occurred in ten weeks. The patient died of coronary thrombosis five years later, without evidence of recurrence of the tumor.2 In a review from the Mayo Clinic (1933) Buie and