Similarities between a predicted secondary structure for the M1 RNA ribozyme and the tRNA binding center of 16 S rRNA from E. coli
- 17 August 1987
- journal article
- Published by Wiley in FEBS Letters
- Vol. 220 (2), 283-287
- https://doi.org/10.1016/0014-5793(87)80830-x
Abstract
We propose a new model for the secondary structure of the M1 RNA component of E. coli RNase P which is based on significant sequence homologies with parts of the E. coli 16 S rRNA. A large domain of the new model resembles closely the secondary structure of the tRNA binding center of 16 S rRNA. We suggest that this domain of M1 RNA when functioning as a ribozyme binds the mature part of the precursor tRNA.Keywords
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