The Primary Structure of Rat Ribosomal Protein L18
- 1 April 1988
- journal article
- research article
- Published by Mary Ann Liebert Inc in DNA
- Vol. 7 (3), 157-162
- https://doi.org/10.1089/dna.1988.7.157
Abstract
The amino acid sequence of rat ribosomal protein L18 was deduced from the sequence of nucleotides in a recombinant cDNA and confirmed from the amino-terminal amino acid sequence of the protein. Ribosomal protein L18 contains 187 amino acids (the amino-terminal methionine is removed after translation of the mRNA) and has a molecular weight of 21,530. Hybridization of the cDNA to digests of nuclear DNA suggests that there are 10–14 copies of the L18 gene. Rat ribosomal protein L18 is homologous to Xenopus laevis L14; the extent of the identity of the amino acid sequences is 87% and for the nucleotides in the coding region of the DNA it is 76%.Keywords
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