CHRONIC REGURGITATION JAUNDICE AS THE PRESENTING SIGN IN SARCOIDOSIS

Abstract

NUMEROUS cases of sarcoidosis have been described in the literature since the disease was first recognized as an entity in 1899. It is well known that the sarcoid lesions may be widely disseminated and frequently involve such structures as skin and mucous membranes, lymph nodes, lungs, bone, the uveoparotid tracts, spleen and liver. However, isolated sarcoidosis of the liver has been described in the literature comparatively infrequently, and in only two instances did we find reports of hepatic involvement with associated regurgitation jaundice. It is the purpose of this paper to present and discuss a case of sarcoidosis of the liver with chronic jaundice. The physical findings, laboratory data and course of this disease were similar to those seen in cholangiolitic cirrhosis of the liver. REPORT OF CASE R. M., a 25 year old Negro woman, was admitted to Michael Reese Hospital in September 1947, with complaints of nausea and