Development of Resistance to Teratocarcinogenesis by Primordial Germ Cells in Mice2

Abstract

Testicular teratomas were experimentally induced in strain 129 genital ridges grafted into the testes of adult strain 129 mice. Fetuses resulting from precisely timed matings were used as donors of genital ridges. The primordial germ cells became resistant to experimental teratocarcinogenesis from 12 days, 12 hours to 13 days, 11 hours of gestation.